Endocrine Abstracts

Mitochondria are complex dynamic intracellular organelles that are responsible for many aspects of muscle metabolism, including energy production via the Krebs cycle, fatty acid beta oxidation, and the respiratory chain and oxidative phosphorylation system; calcium homeostasis; cell signalling via the generation of reactive oxygen species; and regulation of apoptotic cell death. This lecture will discuss muscular phenotypes related to mitochondrial dysfunction, including ocula...